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The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19.

Identifieur interne : 000142 ( Main/Exploration ); précédent : 000141; suivant : 000143

The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19.

Auteurs : Liang Su [République populaire de Chine] ; Xiang Ma [République populaire de Chine] ; Huafeng Yu [République populaire de Chine] ; Zhaohua Zhang [République populaire de Chine] ; Pengfei Bian [République populaire de Chine] ; Yuling Han [République populaire de Chine] ; Jing Sun [République populaire de Chine] ; Yanqin Liu [République populaire de Chine] ; Chun Yang [République populaire de Chine] ; Jin Geng [République populaire de Chine] ; Zhongfa Zhang [République populaire de Chine] ; Zhongtao Gai [République populaire de Chine]

Source :

RBID : pubmed:32208917

Descripteurs français

English descriptors

Abstract

This study aims to analyze the different clinical characteristics between children and their families infected with severe acute respiratory syndrome coronavirus 2. Clinical data from nine children and their 14 families were collected, including general status, clinical, laboratory test, and imaging characteristics. All the children were detected positive result after their families onset. Three children had fever (22.2%) or cough (11.2%) symptoms and six (66.7%) children had no symptom. Among the 14 adult patients, the major symptoms included fever (57.1%), cough (35.7%), chest tightness/pain (21.4%), fatigue (21.4%) and sore throat (7.1%). Nearly 70% of the patients had normal (71.4%) or decreased (28.6%) white blood cell counts, and 50% (7/14) had lymphocytopenia. There were 10 adults (71.4%) showed abnormal imaging. The main manifestations were pulmonary consolidation (70%), nodular shadow (50%), and ground glass opacity (50%). Five discharged children were admitted again because their stool showed positive result in SARS-CoV-2 PCR. COVID-19 in children is mainly caused by family transmission, and their symptoms are mild and prognosis is better than adult. However, their PCR result in stool showed longer time than their families. Because of the mild or asymptomatic clinical process, it is difficult to recognize early for pediatrician and public health staff.

DOI: 10.1080/22221751.2020.1744483
PubMed: 32208917


Affiliations:


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<div type="abstract" xml:lang="en">This study aims to analyze the different clinical characteristics between children and their families infected with severe acute respiratory syndrome coronavirus 2. Clinical data from nine children and their 14 families were collected, including general status, clinical, laboratory test, and imaging characteristics. All the children were detected positive result after their families onset. Three children had fever (22.2%) or cough (11.2%) symptoms and six (66.7%) children had no symptom. Among the 14 adult patients, the major symptoms included fever (57.1%), cough (35.7%), chest tightness/pain (21.4%), fatigue (21.4%) and sore throat (7.1%). Nearly 70% of the patients had normal (71.4%) or decreased (28.6%) white blood cell counts, and 50% (7/14) had lymphocytopenia. There were 10 adults (71.4%) showed abnormal imaging. The main manifestations were pulmonary consolidation (70%), nodular shadow (50%), and ground glass opacity (50%). Five discharged children were admitted again because their stool showed positive result in SARS-CoV-2 PCR. COVID-19 in children is mainly caused by family transmission, and their symptoms are mild and prognosis is better than adult. However, their PCR result in stool showed longer time than their families. Because of the mild or asymptomatic clinical process, it is difficult to recognize early for pediatrician and public health staff.</div>
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<name sortKey="Bian, Pengfei" sort="Bian, Pengfei" uniqKey="Bian P" first="Pengfei" last="Bian">Pengfei Bian</name>
<name sortKey="Gai, Zhongtao" sort="Gai, Zhongtao" uniqKey="Gai Z" first="Zhongtao" last="Gai">Zhongtao Gai</name>
<name sortKey="Geng, Jin" sort="Geng, Jin" uniqKey="Geng J" first="Jin" last="Geng">Jin Geng</name>
<name sortKey="Han, Yuling" sort="Han, Yuling" uniqKey="Han Y" first="Yuling" last="Han">Yuling Han</name>
<name sortKey="Liu, Yanqin" sort="Liu, Yanqin" uniqKey="Liu Y" first="Yanqin" last="Liu">Yanqin Liu</name>
<name sortKey="Ma, Xiang" sort="Ma, Xiang" uniqKey="Ma X" first="Xiang" last="Ma">Xiang Ma</name>
<name sortKey="Sun, Jing" sort="Sun, Jing" uniqKey="Sun J" first="Jing" last="Sun">Jing Sun</name>
<name sortKey="Yang, Chun" sort="Yang, Chun" uniqKey="Yang C" first="Chun" last="Yang">Chun Yang</name>
<name sortKey="Yu, Huafeng" sort="Yu, Huafeng" uniqKey="Yu H" first="Huafeng" last="Yu">Huafeng Yu</name>
<name sortKey="Zhang, Zhaohua" sort="Zhang, Zhaohua" uniqKey="Zhang Z" first="Zhaohua" last="Zhang">Zhaohua Zhang</name>
<name sortKey="Zhang, Zhongfa" sort="Zhang, Zhongfa" uniqKey="Zhang Z" first="Zhongfa" last="Zhang">Zhongfa Zhang</name>
</country>
</tree>
</affiliations>
</record>

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